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Pellicon XL 50 Microfiltration Devices

The Pellicon XL 50 cassette couples Millipore's superior microfiltration membranes with the first truly linearly scalable TFF device for processing small volumes. The Durapore membrane offers ultra-low protein binding and excellent retention performance, which assures reliable and consistent performance.

For linear scalability to exist within a family of TFF devices, the channel geometry (path length and channel height) must be identical for each filter. The Pellicon XL 50 cassette is the only TFF product of this size that can make this claim, providing simple, reliable linear scaleup. The feed and permeate flow channels in every Pellicon XL 50 cassette operates with the same pressure drop, flow velocity, and concentration profile as the larger Pellicon 2 cassettes.

The Labscale TFF System is easy to use for sample preparation while also providing the necessary controls for process development and scale-up work.

Consistent High Flux and High Product Recovery The long established Durapore hydrophilic PVDF microfiltration membrane is well known for its exceptional combination of high flux, low protein binding, and high product recoveries.

Pellicon XL 50 cassettes are 100% integrity tested in manufacturing to ensure consistent and reliable performance.

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Applications

• Harvest, washing, or clarification of cell cultures, lysates, and fermentation broths

• Sample preparation

• Membrane selection studies

• preparation of material for clinical trials

• Small volume manufacturing


Membranes :

Hydrophilic polyvinylidene fluoride (Durapore® membrane)

Screens, Exterior housing, Fittings/connectors and Luer Caps:

Polypropylene


Fittings

Female Luer


Filtration Area

50 cm² (0.05 ft² )


Device Width

3.0 cm (1.2 in.)


Device Length

18.8 cm (7.4 in.)


Hold-up Volume (typical)

3.2 mL


Maximum Operating Pressure

5.6 bar (80 psig)


Optimum Tangential Flow Rate for Polarized Solutions

30 – 50 mL/min


Membrane pH Compatibility

1.5 – 9 (continuous)

1 – 11 (cleaning)


Biocompatibility/Toxicity

All wetted parts have been tested and meet the requirements of the USP Class VI Biological Test for Plastics.


Extractables

Gravimetric extractables level < 7.5 mg/ device after RO water flush. USP oxidizables test negative after RO water flush.


Prefiltration Requirements

Prefiltration of sample using 100 μm nominal pore size filter is recommended.


주문 정보

Hydrophilic PVDF

카탈로그 번호 Filter Code Pore Size
PXDVPPC50 DVPP 0.65 µm
PXGVPPC50 GVPP 0.22 µm
PXHVMPC50 HVMP 0.45 µm
PXVVPPC50 VVPP 0.1 µm


Accessories

카탈로그 번호 Description
XX42RES05 Reservoir, 100 mL, for LabScale
XXPXLFTKT Fittings Adapters and Tubing
XXPXLGAGE Gauge 0-60 psi and Connection Fittings
XXPXLSTND Stand for Pellicon® XL

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